Stress-Related Negative Affectivity and Genetically Altered Serotonin Transporter Function

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Stress-related negative affectivity and genetically altered serotonin transporter function: evidence of synergism in shaping risk of depression.

CONTEXT Genetic moderation of the depression-inducing effects of stressful life events (SLEs) has been reported, but findings suggest that genes may not moderate the effects of SLEs per se but instead may moderate the risk of depression associated with the stable tendency to develop negative emotions in response to minor environmental experiences. OBJECTIVE To examine whether a functional pol...

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ژورنال

عنوان ژورنال: Archives of General Psychiatry

سال: 2006

ISSN: 0003-990X

DOI: 10.1001/archpsyc.63.9.989